If Error 39 points directly to the Virtual USB Bus (not the dongle itself), the bus driver is corrupted.
Even if you are using a virtual bus, having the latest official can sometimes bridge the communication gap. Download the latest GUI runtime from the Thales (formerly Gemalto) website to ensure the underlying USB stack is healthy. Summary Table Impact on Error 39 Recommended Action Windows 11 Disable Core Isolation Old MultiKey Replace with 64-bit signed version USB 3.0 Ports Try a USB 2.0 port/header if using physical keys Best Practices for Mastercam Users Mastercam X7-2022 Virtual Usb Bus Error 39
: This is the most common solution for virtual drivers on Windows 10 and 11. Open Windows Security and navigate to Device Security . Click on Core isolation details . Toggle Memory integrity to Off . Restart your computer to apply the changes. If Error 39 points directly to the Virtual
Navigate to > Advanced Options > Startup Settings > Restart . Press F7 to select "Disable driver signature enforcement." Once booted, try reinstalling the virtual USB driver. 3. Manual Registry Cleanup Summary Table Impact on Error 39 Recommended Action