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: The power struggle between Michael and Abruzzi showcases the shift from Michael being in control to him being a passenger in a much more dangerous game. : Like many episodes in Season 1, "

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The episode begins with a mysterious and deadly virus spreading through Fox River State Penitentiary. The virus causes its victims to have violent outbursts, leading to chaos and panic among the inmates and the guards. Michael Scofield (played by Wentworth Miller) and his fellow inmates must find a way to survive and possibly cure the virus. : The power struggle between Michael and Abruzzi