If you are struggling to get the highly compressed ISO working, consider these that run on PSP via native compatibility:

The survival horror genre has been a staple of the gaming industry for decades, and one of the most iconic franchises in this genre is Resident Evil. Developed by Capcom, Resident Evil has been thrilling gamers with its intense action, horror elements, and engaging storyline since its inception in 1996. One of the most critically acclaimed games in the series is Resident Evil 4, which was initially released for the Nintendo GameCube in 2005. However, in this article, we will focus on the PSP (PlayStation Portable) version of Resident Evil 4, specifically the highly compressed high-quality ISO.

If you download a file claiming to be Resident Evil 4 for PSP, it is usually one of three things: